Hyperkalemic Periodic Paralysis and Paramyotonia Congenita can occur singly or in combination.
While most attacks of Hyperkalemic Periodic Paralysis are brief and do not require emergency intervention, occasionally the serum potassium level will be high enough to cause cardiac distress, or muscle stiffness may interfere with respiration. Attacks of weakness in Paramytonia Congenita are usually mild to moderate in severity, but myotonia of chest, diaphragm and throat muscles can be life-threatening under some circumstances.
A free workbook to download for those who are in the diagnostic process, contains information on each type of PP, diagnostic testing, available therapies, how to determine episode triggers and work out a management plan. download here
The normal renal response when hypokalemia is due to non-renal causes is a TTKG <2, where a TTKG >5 is indicative of increased secretion of K+ in the cortical collecting ducts. Thus a transtubular potassium concentration gradient (TTKG) of greater than 3.0 indicates hypokalemia of renal origin, while a value below 2.0 indicates intracellular shift of K+, as found in ion channelopathy hypokalemic periodic paralysis.
This information is based on diet recommendations found in many medical journal and textbook articles about Hyperkalemic Periodic Paralysis. (HyperKPP). According to physicians and dieticians those with HyperKPP should follow a diet which is high in carbohydrates and low in potassium. Because muscle tissue is stressed in the periodic paralyses it is also essential that patients obtain liberal amounts of high-quality protein.
This information is based on a diet designed at the National Institutes of Health in the 1960s for a young man with Hypokalemic Periodic Paralysis (HypoKPP). According to the NIH physicians and dietician Mary R. Emerson, plus many other medical authorities, those with HypoKPP should follow a diet which is high in protein, low in carbohydrate, and low in sodium.
Thyrotoxic periodic paralysis (THKPP) is an uncommon disorder characterized by simultaneous thyrotoxicosis, hypokalemia, and paralysis that occurs primarily in males of Asian descent, including patients of Japanese, Chinese, Vietnamese, Korean and Filipino ancestry.
The information on this site is based on current medical knowledge but should never at any time be substituted for the advice and care of a properly qualified medical consultant. For medical advice seek the services of a physician.