Pregnancy and Birth in HypoKPP

Submitted by deb on Sun, 06/26/2011 – 23:58 Part Two Case Studies – HypoKPP Patient #1 Three Pregnancies: Familial HypoKPP Symptoms began at age of 13 years with three paralytic episodes of 48-72 hour duration. Are your symptoms worse with your menses? No Pregnancy No 1: Age 20 Diagnosed at time of this pregnancy: Yes Episodes consisted of…

Pain in the Periodic Paralyses

Submitted by deb on Sat, 06/25/2011 – 23:22 Pain Often Overlooked Pain is an often overlooked component of the periodic paralyses. Patients who report muscle pain in association with their episodes are too often told that the periodic paralyses are not painful despite many authoritative reports to the contrary. In fact the pain which accompanies the periodic…

Pregnancy and Birth in Andersen-Tawil Syndrome

Submitted by deb on Mon, 06/27/2011 – 00:09 Part Four Case Studies – ATS Patient #18 Two Pregnancies: ATS2; Hypokalemic episodes Symptoms began in early childhood; Are your symptoms worse with your menses? Yes Pregnancy No 1: Age 32 Diagnosed at time of this pregnancy: No Episodes consisted of daily moderate weakness, some paralysis. Hospitalized due to right-sided paralysis…

Malignant Hyperthermia

Submitted by deb on Mon, 06/27/2011 – 19:16 Periodic Paralysis Patients at Increased Risk of MH Patients with Hyperkalemic periodic paralysis and Paramyotonia Congenita are at increased risk for Malignant Hyperthermia (MH) during surgery.  Patients with all types of periodic paralysis often become paralyzed during or after surgery, from stress, chilling in the OR and the use…

Chart Comparing Periodic Paralyses

Submitted by deb on Sat, 07/02/2011 – 20:58 This chart allows comparison of the forms of primary periodic paralysis, symptoms, clinical and cardiac signs, effect of potassium, triggers and therapies.  Form Effect of K+ Age at onset Triggers Relieves Attack Length Myotonia? Hypertrophy Weakness between attacks EKG during attacks Therapies Thyrotoxic HypoKalemic Periodic Paralysis  Relieves weakness At…