Journal Articles / Scientific Papers

  • *Hyperkalemic Periodic Paralysis FAQ

    Patients with Hyperkalemic PP (HyperKPP) develop paralysis or weakness (and sometimes muscle stiffness) when they eat potassium-rich food. This is also referred to as ‘potassium sensitive’ periodic paralysis. This is usually called Hyperkalemic Periodic Paralysis because most patients’ potassium levels rise during attacks. HyperKPP is due to a mutation in the sodium channel.  Hyperkalemic Periodic…

  • *GUIDELINES ved indlaeggelse for Hypokalemisk Periodika Paralyse Patient

    Navn & CPRnr Højde:  cm Vægt:  kg Adresse: Egen læge: Emergency contact: navn (tlf: ) + evt personlige assistent og/eller ledsager: OPMÆRKSOMHED: patienten placeres i aflåst sideleje for at holde luftveje frie/åbne ved anfald. De paralytiske anfald kan hurtigt udvikle sig til lammelse og respirationssvigt. – overvåg patienten nøje. (Lammede patienter kan synes at være…

  • *Hospital Management Guidelines – HypoKPP

    Patient’s Name: ______________________________________________ Birthdate: _________________________Height: ____________Weight: _______ Address:________________________________________________________ _________________________________________________________________ Primary Physician: _____________________________________________ Physician Phone: _______________________ FAX: ______________________ Emergency contact:  Your emergency contact should be someone who can speak for you when you cannot advocate for yourself. Name: ____________________________________________                                  …

  • *Determining the Origin of Hypokalemic Paralysis

    Using the Transtubular Potassium Concentration Gradient to Determine the Origin of Hypokalemic Paralysis Many patients with hypokalemic paralysis live in diagnostic limbo for years without appropriate testing and therapy. Since time is muscle in the channelopathies, patients need speedy diagnosis and treatment. Repeated studies have shown that the transtubular potassium concentration gradient (TTKG), easily performed…

  • *Hypokalemic Periodic Paralysis

    Physician’s Summary Hypokalemic periodic paralysis (HypoKPP) is one of the primary forms of periodic paralysis, caused by one or more mutations in the calcium, sodium or potassium ion channels in muscle membrane. Features of Hypokalemic Periodic Paralysis There are two forms of HypoKPP, a paralytic form and a myopathic form. The paralytic form is more…

  • *Hospital Management Guidelines for Thyrotoxic Hypokalemic Paralysis

    Patients with Thyrotoxic Hypokalemic Paralysis Patient’s Name:________________________________________________ Birthdate: ________Height: _______Weight: _______ Address: ____________________________________________________ ______________________________________________________________ Primary Physician:___________________________________________ Physician contact: ___________________________________________ FAX:_______________________________ Emergency contact:  Your emergency contact should be someone who can speak for you when you cannot advocate for yourself. Name:_________________________________________________________                     Relationship:_________________________________________________ home phone#  _________________  cell#_____________________                      PRECAUTIONS: Place patient in coma position to avoid aspiration during…

  • *The Man Who Couldn’t Walk

    Case Study of Thyrotoxic Hypokalemic Paralysis A case study Originally published in Lifeline; Newsletter of The California Chapter of the American College of Emergency Physicians Christopher Fee, MD and Susan B. Promes, MD FACEP Alameda County California Medical Center, Highland General Hospital Acute weakness is a common patient complaint in the emergency department with a…

  • *Thyrotoxic Hypokalemic Periodic Paralysis – A Physicians Summary

    A Physician’s Summary Clinical Synopsis Thyrotoxic periodic paralysis (THKPP) is an uncommon disorder characterized by simultaneous thyrotoxicosis, hypokalemia, and paralysis that occurs primarily in males of Asian descent, including patients of Japanese, Chinese, Vietnamese, Korean, and Filipino ancestry.  It most commonly presents as sudden onset weakness in the proximal muscles. It is reversible when treated…

  • *Thyrotoxic HypoKPP FAQs for Patients

    What is Thyrotoxic Hypokalemic Periodic Paralysis? Thyrotoxic Hyperkalemic Periodic Paralysis (TPP) is an uncommon disorder with three characteristics which occur at the same time:   ​TPP occurs most often in males of Asian descent, including Japanese, Chinese, Vietnamese, Korean and Filipinos. It also occurs more frequently in those of Native American and Latin American descent, but…