Submitted by deb on Mon, 06/27/2011 – 04:39 The regular colonoscopy prep can cause a hypokalemic episode in a patient with hypokalemic periodic paralysis. This colonoscopy prep, adapted to avoid hypokalemia, has been used by numerous patients with HypoKPP on the HKPP Listserv without provoking an episode afterwards. Colonoscopy Prep: Day 1 Normal diet with an herbal tea…
Submitted by deb on Fri, 03/01/2013 – 17:49 Severe respiratory phenotype caused by a de novo Arg528Gly mutation in the CACNA1S gene in a patient with hypokalemic periodic paralysis. Authors Kil TH, et al. Journal: Eur J Paediatr Neurol. 2010 May;14(3):278-81. doi: 10.1016/j.ejpn.2009.08.004. Epub 2009 Oct 12. Affiliation: Department of Pediatrics, College of Medicine, Konyang University, 685…
Submitted by deb on Mon, 06/27/2011 – 23:16 Are Weakness and Fatigue Between Paralytic Attacks Symptoms of Periodic Paralysis? Patients frequently report that their physician denies that muscle weakness and fatigue between paralytic attacks are a part of periodic paralysis. While it was reported in the past that patients with periodic paralysis had ‘normal’ muscle strength and…
Submitted by deb on Thu, 06/21/2012 – 16:31 1) Patient has “attacks” of weakness and/or floppy paralysis. 2) First attacks occur by the age of 16 in 65% of patients. 3) Attacks follow triggering events (vigorous exercise, intense stress, fright) or a meal high in carbohydrate and/or sodium (baked goods, pizza, Chinese food, sugar-sweetened soda, beer, etc.)….
Submitted by deb on Mon, 06/27/2011 – 00:04 Part Three Case Studies – HyperKPP and PMC Patient #11 Two Pregnancies: Familial HyperKPP and PMC Von Eulenburg Symptoms began at age of 11 years Are your symptoms worse with your menses? No Pregnancy No 1: Age 27 Diagnosed at time of this pregnancy: No Episodes consisted of moderate…
Submitted by deb on Mon, 06/27/2011 – 20:16 Patients with Sodium channel HyperKPP and PMC mutations are at increased risk of Malignant Hyperthermia; It has long been recognized that patients with hyperkalemic periodic paralysis are at increased risk for Malignant Hyperthermia (MH) during surgery, showing as fulminant muscle rigidity as seen in the jaw muscles, rhabdomyolysis, hypercarbia, and…
Submitted by deb on Sun, 07/17/2011 – 21:14 This information is based on diet recommendations found in many medical journal and textbook articles about Hyperkalemic Periodic Paralysis. (HyperKPP). According to physicians and dieticians those with HyperKPP should follow a diet which is high in carbohydrates and low in potassium. Because muscle tissue is stressed in the periodic…
Submitted by deb on Tue, 06/28/2011 – 21:14 Clinical Signs Hyperkalemic Periodic Paralysis is a genetically determined disorder which causes attacks of weakness and flaccid paralysis. Attacks last from 10 min to 1 hour, very rarely up to 1-2 days. Some patients experience only a few attacks over their lifetime, others have attacks every day. Diagnosis is…
Submitted by deb on Wed, 10/12/2011 – 23:03 Irm’s Story The PPI’s Client Services Representative in The Netherlands is Irm. Irm and her son were clinically diagnosed with HypoKPP-plus in Germany in September 2011, but she has had symptoms since she was a young child. At the age of 7, she told her parents, “My head is…
Submitted by deb on Sun, 06/26/2011 – 23:58 Part Two Case Studies – HypoKPP Patient #1 Three Pregnancies: Familial HypoKPP Symptoms began at age of 13 years with three paralytic episodes of 48-72 hour duration. Are your symptoms worse with your menses? No Pregnancy No 1: Age 20 Diagnosed at time of this pregnancy: Yes Episodes consisted of…