Submitted by deb on Wed, 03/13/2013 – 18:08
Leaky channels make weak muscles: Mutations in the skeletal muscle voltage-gated calcium channel (CaV 1.1) have been associated with hypokalemic periodic paralysis, but how these mutations cause the symptoms of the disorder has always been unclear. In this article the authors describe how they used mice with the CaV 1.1 mutation to investigate how the mutation causes the features of HypoKPP.
Severe respiratory symptoms in a patient with HypoKPP: Paralytic attacks in HypoKPP generally spare the respiratory muscles and the heart. Here, we report the case of a 16-year-old boy who presented with frequent respiratory insufficiency during the severe attacks.
Ventricular Tachyarrhythmias in a Patient with Andersen-Tawil Syndrome; An 18-year-old female patient arrives in the ER with life-threatening cardiac arrhythmia and acute respiratory distress and is diagnosed with ATS.