What is Andersen-Tawil Syndrome? Andersen-Tawil Syndrome (ATS) is a rare inherited disorder which causes episodes of paralysis or weakness, heart rhythm irregularities including a prolonged QT interval which makes the heart more likely to experience tachycardia (a regular but too rapid heart rate) or dangerous irregular heart rates. ATS typically causes some physical characteristics as…
A Physician’s Summary Andersen-Tawil Syndrome (ATS) is a genetic disorder which causes a distinctive pattern of features; 1) Episodes of muscle weakness and/or flaccid paralysis (i.e periodic paralysis) 2) Certain kinds of heart rhythm disturbances and 3) Differences in facial and body structure. Clinical signs: Most ATS patients begin to have symptoms by the time…
Submitted by ian on Tue, 06/21/2011 – 22:55 The periodic paralyses are a group of rare inherited disorders that cause temporary episodes of muscle weakness or paralysis. Periodic Paralysis is found in all races and in both sexes. Some patients have their first attack within minutes of birth, but a few don’t have symptoms until they are…
Submitted by deb on Tue, 04/12/2016 – 22:54 Adverse reactions to anaesthesia, including life-threatening events, are a serious concern for patients with Periodic Paralysis Disorders. Many of our patients report serious events associated with anesthesia and side effects which may linger for days to months. There is rarely time for a surgical team to comb through journals…
Submitted by deb on Tue, 07/03/2012 – 18:45 Measuring quality of life impairment in skeletal muscle channelopathies. Eur J Neurol. 2012 May 19. doi: 10.1111/j.1468-1331.2012.03751.x. [Epub ahead of print] Sansone VA, Ricci C, Montanari M, Apolone G, Rose M, Meola G; INQoL Group. SourceDepartment of Neurology, University of Milan, IRCCS Policlinico San Donato, Milan, Italy. Abstract Link to…
Submitted by deb on Sat, 07/02/2011 – 18:02 Introduction: The major features found in all the periodic paralyses are: 1. Attacks almost always begin before the age of 25, though occasionally later in life. ATS patients can develop first symptoms at any age. 2. Serum potassium fluctuates shortly before an attack, but serum potassium level will normalize…
Submitted by deb on Mon, 04/16/2018 – 21:17 Andersen-Tawil Syndrome (ATS) is a genetic disorder which causes a distinctive pattern of features; 1) Episodes of muscle weakness and/or flaccid paralysis (i.e periodic paralysis) 2) Certain kinds of heart rhythm disturbances and 3) Differences in facial and body structure. Clinical signs: Most ATS patients begin to have symptoms by…
Submitted by deb on Sat, 06/25/2011 – 18:27 What is Andersen-Tawil Syndrome? Andersen-Tawil Syndrome (ATS) is a rare inherited disorder which causes episodes of paralysis or weakness. It has been diagnosed in only a few hundred families in the world. It was only recognized as a separate disorder in 1971. ATS causes attacks of muscle weakness and…
Submitted by deb on Mon, 06/27/2011 – 04:50 Patients who take potassium chloride long-term, i.e., are at risk for developing vitamin B-12 deficiency. Potassium supplements such as K-Dur, Micro-K, Slow-K, K-Lyte, etc. interfere with the absorption of vitamin B-12 and can eventually lead to the depletion of body stores of this crucial vitamin. 1, 2, 3 Unlike other…
Submitted by Anonymous (not verified) on Mon, 05/08/2017 – 06:25 This comprehensive article is from the National Organization for Rare Disorders (NORD) NORD gratefully acknowledges Rabi Tawil, MD, University of Rochester Medical Center, Professor of Neurology for assistance in the preparation of this report. Synonyms of Andersen-Tawil Syndrome Andersen SyndromeATSLong QT Syndrome 7LQTS7General Discussion Summary Andersen-Tawil syndrome…