Provided by Frank Lehmann-Horn MD, PhD From: Lehmann-Horn F, Rüdel R, Jurkat-Rott K. Chapter 46: Nondystrophic myotonias and periodic paralyses. In: Myology, edited by AG Engel, C Franzini-Armstrong. McGraw-Hill, New York, 3rd edition, 2004, pp. 1257-1300. and Klingler W, Lehmann-Horn, Jurkat-Rott K. Complications of anesthesia in neuromuscular disorders. Neuromuscular Disord, 15:195-206, 2005. In patients with…
Paralytic attacks of Hypokalemic Periodic Paralysis can cause cardiac and/or respiratory distress or arrest. Patients may become unable to cough and may choke on their own secretions or on vomit. Attacks of profound paralysis or ones in which there is cardiac or respiratory distress require immediate emergency medical attention. First Actions: Monitoring Measure serum K+…
Submitted by deb on Tue, 06/28/2011 – 02:56 The Importance to Physicians of Support Groups for Rare Conditions The Genetic Drift Vol. 8: Winter, 1992 Consumer Issues in Genetics Services by Jack Dolcourt, M.D. Neonatologist Support groups have traditionally helped fill the void between the medical system and the daily grind of the everyday world. Support groups…
Submitted by deb on Wed, 07/20/2011 – 19:51 Communication is key: Stephen Wilkins, MPH, writes of improving practice management through improved patient/physician communication and its impact on care, in Mind the Gap. Practical aspects in the management of hypokalemic periodic paralysis. Author: Jacob O Levitt MD; Management considerations in hypokalemic periodic paralysis include accurate diagnosis, potassium dosage for acute attacks,…
Submitted by deb on Fri, 01/16/2015 – 00:37 Ding Z, Liu M, Cui L. Reference value of long-time exercise test in the diagnosis of primary periodic paralysis. Chin Med J (Engl). 2014;127(18):3219-23. Abstract BACKGROUND:The long-time exercise test (ET) is used to diagnose the primary periodic paralyses (PPs). However the reference values of ET are many and various….
Submitted by deb on Sun, 06/26/2011 – 23:58 Part Two Case Studies – HypoKPP Patient #1 Three Pregnancies: Familial HypoKPP Symptoms began at age of 13 years with three paralytic episodes of 48-72 hour duration. Are your symptoms worse with your menses? No Pregnancy No 1: Age 20 Diagnosed at time of this pregnancy: Yes Episodes consisted of…
Submitted by deb on Mon, 01/21/2013 – 18:12 This article is dedicated to the memory of Aleksandr Batutenko, a person who was not afraid to declare publicly his rare disease. It was written by Aleksandr Batutenko’s wife Nadezhda, and it is published here with her permission. Aleksandr was a brave young man who lost his life trying…
Management Strategies For Hypokalemic Periodic Paralysis Submitted by deb on Fri, 08/26/2011 – 20:09 In 2009 Professor Dr. Frank Lehmann-Horn of Ulm University, Ulm Germany, gave a presentation on managing hypokalemic periodic paralysis at the Periodic Paralysis Association’s conference held in Orlando Florida. This presentation contained so much valuable information in such a compact and understandable format that we asked…
Submitted by deb on Tue, 07/03/2012 – 18:31 Penn State researcher counts the ways poetess Browning may have had rare diseaseBy Tom Avril; Philadephia Inquirer Staff Writer Scholars have proposed a number of explanations for the muscle weakness and other ailments that plagued the Victorian poet Elizabeth Barrett Browning. But none of these after-the-fact diagnoses – from anxiety…
Submitted by deb on Tue, 03/05/2013 – 00:34 Neurology. 2013 Feb 20. [Epub ahead of print]Bumetanide prevents transient decreases in muscle force in murine hypokalemic periodic paralysis.Wu F, Mi W, Cannon SC. Source: From the Department of Neurology and Neurotherapeutics (F.W., W.M., S.C.C.) and Program in Neuroscience (S.C.C.), UT Southwestern Medical Center, Dallas, TX. Abstract OBJECTIVE: To…