The Compound Muscle Action Potential (CMAP) test (aka the Exercise EMG) is used to diagnose the periodic paralyses. When done correctly this test is reported to positively identify 70%-80% of patients. The CMAP test is based on the observation that patients with Periodic Paralysis have a greater than normal increase in the compound muscle action…
Danish version of “Emergency Treatment of the Hypokalemic Paralytic Attack” Første skridt: 1. Åndedræts- eller hjerteanfald er mulige 2. Tjek hjerte og vejrtrækning – dilatation i hjertet kan forårsage høj puls og lavt blodtryk. 3. Foretag måling af hjerterytme/EKG. 4. Mål elektrolytter for at bestemme serum K+ 5. Giv ilt – blodprøve fra fingeren afspejler…
Provided by Frank Lehmann-Horn MD, PhD From: Lehmann-Horn F, Rüdel R, Jurkat-Rott K. Chapter 46: Nondystrophic myotonias and periodic paralyses. In: Myology, edited by AG Engel, C Franzini-Armstrong. McGraw-Hill, New York, 3rd edition, 2004, pp. 1257-1300. and Klingler W, Lehmann-Horn, Jurkat-Rott K. Complications of anesthesia in neuromuscular disorders. Neuromuscular Disord, 15:195-206, 2005. In patients with…
Paralytic attacks of Hypokalemic Periodic Paralysis can cause cardiac and/or respiratory distress or arrest. Patients may become unable to cough and may choke on their own secretions or on vomit. Attacks of profound paralysis or ones in which there is cardiac or respiratory distress require immediate emergency medical attention. First Actions: Monitoring Measure serum K+…
Emergency Treatment of the HyperKalemic Periodic Paralysis and/or Paramyotonia Congenita Attack First Actions: Hyperkalemic Periodic Paralysis and Paramyotonia Congenita can occur singly or in combination. While most attacks of Hyperkalemic Periodic Paralysis are brief and do not require emergency intervention, occasionally the serum potassium level will be high enough to cause cardiac distress, or muscle stiffness may…
First Actions: Monitor closely, weakness can rapidly progress to paralysis, torsades de pointes, cardiac arrest and respiratory failure. Paralyzed patients may appear to be unconscious, but are awake and aware. Do not assume they cannot feel pain or hear conversations. Andersen-Tawil syndrome (ATS) is characterized by the triad of episodic flaccid muscle weakness, distinctive dysmorphic…
First Actions: A True Endocrine Emergency Patients with Thyrotoxic Hypokalemic Periodic Paralysis typically present at the ER with an acute episode of paralysis involving the muscles of the extremities and limb girdles. The lower limbs are more frequently and severely involved than the upper. Weakness may be asymmetrical. Proximal strength is more severely impaired than…
Submitted by deb on Sun, 07/17/2011 – 19:37 Clinical Synopsis Thyrotoxic periodic paralysis (THKPP) is an uncommon disorder characterized by simultaneous thyrotoxicosis, hypokalemia, and paralysis that occurs primarily in males of Asian descent, including patients of Japanese, Chinese, Vietnamese, Korean and Filipino ancestry. Kilpatrick et al. (1994) found six reports of thyrotoxic hypokalemic periodic paralysis in African-Americans…
Submitted by deb on Sun, 06/26/2011 – 00:05 Paramyotonia Congenita (PMC) is one of the periodic paralyses caused by mutations in the sodium channel. PMC causes muscle stiffness (myotonia) which is made worse by chilling or activity. Myotonia usually eases when the patients moves about, or “warms up” through physical activity. In PMC myotonia develops during activity, which is paradoxical or…
Submitted by deb on Sun, 11/09/2014 – 21:32 Focal and abnormally persistent paralysis associated with congenital paramyotonia. Magot A1, David A2, Sternberg D3, Péréon Y1. British Medical Journal Case Report 2014 Jun 17;2014. Abstract Mutations of the skeletal muscle voltage-gated sodium channel (NaV1.4) are an established cause of several clinically distinct forms of periodic paralysis and myotonia….