Physician’s Summary Paramyotonia Congenita (PMC) is one of the periodic paralyses caused by mutations in the sodium channel. PMC causes muscle stiffness (myotonia) which is made worse by chilling or activity. Myotonia usually eases when the patients moves about, or “warms up” through physical activity. In PMC myotonia develops during activity, which is paradoxical or…
Paramyotonia congenita (PMC) is a muscle disorder which causes muscle stiffness (myotonia) that appears during exercise and becomes much more severe upon exposure to cold. The myotonia which occurs during attacks of PMC may be so severe that the patient cannot inhale and exhale properly, and movement becomes difficult. The medical term myotonia means that…
Submitted by deb on Sun, 06/26/2011 – 00:05 Paramyotonia Congenita (PMC) is one of the periodic paralyses caused by mutations in the sodium channel. PMC causes muscle stiffness (myotonia) which is made worse by chilling or activity. Myotonia usually eases when the patients moves about, or “warms up” through physical activity. In PMC myotonia develops during activity, which is paradoxical or…
Submitted by deb on Sun, 11/09/2014 – 21:32 Focal and abnormally persistent paralysis associated with congenital paramyotonia. Magot A1, David A2, Sternberg D3, Péréon Y1. British Medical Journal Case Report 2014 Jun 17;2014. Abstract Mutations of the skeletal muscle voltage-gated sodium channel (NaV1.4) are an established cause of several clinically distinct forms of periodic paralysis and myotonia….
Submitted by deb on Mon, 06/27/2011 – 23:16 Are Weakness and Fatigue Between Paralytic Attacks Symptoms of Periodic Paralysis? Patients frequently report that their physician denies that muscle weakness and fatigue between paralytic attacks are a part of periodic paralysis. While it was reported in the past that patients with periodic paralysis had ‘normal’ muscle strength and…
Submitted by deb on Mon, 06/27/2011 – 00:04 Part Three Case Studies – HyperKPP and PMC Patient #11 Two Pregnancies: Familial HyperKPP and PMC Von Eulenburg Symptoms began at age of 11 years Are your symptoms worse with your menses? No Pregnancy No 1: Age 27 Diagnosed at time of this pregnancy: No Episodes consisted of moderate…
Submitted by deb on Mon, 06/27/2011 – 20:16 Patients with Sodium channel HyperKPP and PMC mutations are at increased risk of Malignant Hyperthermia; It has long been recognized that patients with hyperkalemic periodic paralysis are at increased risk for Malignant Hyperthermia (MH) during surgery, showing as fulminant muscle rigidity as seen in the jaw muscles, rhabdomyolysis, hypercarbia, and…
Submitted by deb on Sun, 07/17/2011 – 21:14 This information is based on diet recommendations found in many medical journal and textbook articles about Hyperkalemic Periodic Paralysis. (HyperKPP). According to physicians and dieticians those with HyperKPP should follow a diet which is high in carbohydrates and low in potassium. Because muscle tissue is stressed in the periodic…
Submitted by deb on Mon, 06/27/2011 – 00:04 Part Three Case Studies – HyperKPP and PMC Patient #11 Two Pregnancies: Familial HyperKPP and PMC Von Eulenburg Symptoms began at age of 11 years Are your symptoms worse with your menses? No Pregnancy No 1: Age 27 Diagnosed at time of this pregnancy: No Episodes consisted of moderate…
Submitted by deb on Sun, 07/03/2011 – 23:34 When I’m in the middle of an abortive attack meal planning goes right out the window. I can look at a fridge and pantry full of food and not be able to figure out what to do with any of it. The only way to avoid feeding the family…